![]() | Home | Current Issue | Archives | Subscriptions | Contact Us ![]() Log In | Search | Author Index | Advertising |
Radioimmunotherapy for disseminated lymphomaJames S. Welsh, Christine Berta
Abstract: Most patients with low-grade non-Hodgkin's lymphoma present with advanced-stage disease that is not considered curable by current treatment approaches, including chemotherapy. Radioimmunotherapy uses radioisotopes conjugated to monoclonal antibodies directed against tumor cell antigens. The antibody seeks out tumor cells at disseminated sites, where the radioisotope provides short-range ionizing radiation over a period of hours to days to achieve tumor cell apoptosis. Through the "crossfire" effect, radiation is also able to eradicate nearby tumor cells that do not bear the target antigen. Encouraging results have been reported from recent clinical trials using several radioimmunoconjugates. |
Science & Medicine, Inc. P.O. Box 313, Narberth, PA 19072 (610) 660-8097 (800) 888-0028 fax (610) 660-0348 e-mail editor@sciandmed.com | See our other journal: Medical Problems of Performing Artists. Home | Current Issue | Archives | Subscriptions | Contact Us ![]() Log In | Search | Author Index | Advertising |
Copyright © 2002-2019, Science & Medicine, Inc.