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Tumor markers

Stewart Sell
From: Science & Medicine: Volume 7 Number 2: Page 8 (April 2000)

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Abstract: Tumorm markers are classically defined as substances produced by tumor cells but not by normal adult cells. If released into the circulation, markers can be detected immunologically or biochemically, and cell surface markers are found by immunologic tests. Several such markers are in routine use to diagnose cancer and to measure the effectiveness of therapy. Efforts to discover markers specific to individual tumors and use them as a bais for autologous tumor vaccines have had limited success to date. More broadly, the genetic changes that cause cancers to for can also be considered markers, especially in evaluating the results of therapy.

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