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Bone morphogenic proteins

Caroline Demers, Reggie C. Hamdy
From: Science & Medicine: Volume 6 Number 6: Page 8 (December 1999)

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Abstract: Formation of tissue during embryonic bone development can be recapitulated by implanting demineralized bone matrix in extraskeletal sites. Inductio of bone formation is a property of a group of proteins that appear to also govern other evelopmental functions. Expression cloning of some of these bone morphogenetic proteins has provided evidence that they can be useful in clinical applications, given a suitable carrier that forms a scaffold for new bone growth.

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