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Estrogen is a male and female hormone

George G.J.M. Kuiper, Mats Carlquist, Jan-Ake Gustafsson
From: Science & Medicine: Volume 5 Number 4: Page 36 (August 1998)

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Abstract: The so-called female sex hormone, estrogen is best known for its cdritical role in influencing female secondary sexual characteristics, reproductive cycle, fertility, and maintenance of pregnancy. Less well known are the important actions of estrogen in male tissues, such as the prostate, testis, and epididymis. Estrogens are assential for the normal development of bone tissue in the male, in addition to their well-known role in female bone. The recent unexpected discovery of a second estrogen receptor protein has advanced understanding of the mechanisms underlying estrogen signaling. The challenge is to use this knowledge for the development of the next generation of drugs targeted to the estrogen receptor.

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