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Human papillomaviruses

Rhoda M. Alani, Karl Munger
From: Science & Medicine: Volume 5 Number 3: Page 28 (June 1998)

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Abstract: Certain types of human papillomavirus can be isolated from most cervical carcinomas. These HPV's contribute to carcinogenic progression by blocking the actions of cellular proteins that normally function to prevent cells from dividing. Investigations into the mechanisms of carcinogenesis induced by HPV infections have provided a clear understanding of the growth-regulating pathways that are disturbed during HPV-associated malignant conversion as well as the defects in the immune response that permit the infection to become established.

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