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Tissue culture in microgravity

Paul H. Duray, Steven J. Hatfill, Neal R. Pellis
From: Science & Medicine: Volume 4 Number 3: Page 46 (June 1997)

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Abstract: Attempts to simulate normal tissue microenvironments in vitro have been thwarted by the complexity and plasticity of the extracellular matrix, which is important in regulating cytoskeletal and nuclear matrix proteins. Gravity is one of the problems, tending to separate compnents that should be kept together. sor space shuttle experiments, NASA engineers devised a double-walled rotating bioreactor, which is proving to be a useful tissue culture device on earth as well as in space.

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