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The immunology of inflammatory arthritis

Samuel M. Behar, Steven A. Porcelli
From: Science & Medicine: Volume 3 Number 6: Page 12 (December 1996)

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Abstract: Inflammation of the joints is frequently a prominent clinical feature of diseases that seem to be caused by abnormal immune respnses. Many types of arthritis have been traditionally viewed as autoimmune diseases affecting the joints. Recent studies suggest that hypersensitivity to microbial antigens may also contribute to the development of some types of inflammatory arthritis and may hold the key to understanding the complex interplay between genetic and environmental factors that predispose some people to develop these diseases.

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