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The fish oil puzzle

Scott H. Goodnight
From: Science & Medicine: Volume 3 Number 5: Page 42 (October 1996)

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Abstract: Studies on the effects of a traditional Eskimo diet on plasma lipids and platelet function coincided with elucidation of the mechanisms of prostagandin synthesis in platelets and vascular endothelial cells. When the two lines of investigation joined, the possibility that fish oil might reduce cardiovascular mortality set off a debate that has continued for almost 20 years. Bits of information suggest that eating even small amounts of fish can be beneficial, but how tiny qyantities of dietary n-3 fatty acids might be proective has been difficult to determine. Now it seems likely that the mechanism is an antiarrhythmic effect arising from modulation of calcium ion flux.

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