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Antiplatelet therapy

Richard C. Becker
From: Science & Medicine: Volume 3 Number 4: Page 12 (August 1996)

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Abstract: It is widely appreciated that platelets play a pivotal role in the initiation of intravascular thrombosis; however, they also represent a key element in physiologic hemostasis. Therein lies the dilemma of preventing "bad" blood clots while allowing "good"blood clots to form and offer protection from serious bleeding. The major target for newer antiplatelet therapies is the platelet surface glycoprotein IIb/IIIa receptor, which represents the final common pathway for platelet aggregation. Encouraging findings from early clinical experience have fostered a wide-scale search for a perfect platelet inhibitor.

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