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Preterm birth

Paul C. MacDonald, M. Linette Casey
From: Science & Medicine: Volume 3 Number 2: Page 42 (April 1996)

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Abstract: Almost until delivery, the myometrium is maintained in a quiescent state by progesterone, in humans and in other mammals. The end of this phase of parturition is heralded in other species, but not in humans, by a decline in progesteron synthesis. What triggers the start of active uterine contractions in human pregnancy , at term or preterm, is still unknown, in spite of efforts throughout this century to discover physiologic links. "Silent infections," often blamed for preterm births, are unlikely to be responsible.

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