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Retinoids in differentiation and neoplasia

Luigi M. De Luca, Nadine Darwiche, Carol S. Jones, Giorgio Scita
From: Science & Medicine: Volume 2 Number 4: Page 28 (August 1995)

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Abstract: Retinoids are necessary for a variety of physiologic processes. Identification of the retinoid receptor families was the first step to understanding retinoid function, other than in visionn, at the molecular level. Laboratories focusing on embryogenesis and those concentrating on cancer treatment and prevention have made substantial strides in applying the basic science of retinoids and their receptors to clinical problems. Diagnosis and monitoing of acute promyelocytic leukemia and its treatment with retinoic acid is a clinically useful consequence.

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