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The extracellular matrix

Lynn Y. Sakai
From: Science & Medicine: Volume 2 Number 3: Page 58 (June 1995)

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Abstract: The extracellular matrix is populated by distinct molecules that perform nonredundant functions and contribyte to the structural integrity of connective tissues. These molecules include many types of collagen and families of noncollagenous peptides. Advancing molecular technology has allowed the tracing of geitable disorders of connective tissue to defects in genes coding for extracellular matrix molecules. Many of the collagens are now linked with specific diseases, and discovery and analysis of several of the noncollagenous molecules, for example fibrillin, continue to expand the field.

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