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Airway Inflammation in Asthma

Aparna Kumar, William Busse
From: Science & Medicine: Volume 2 Number 2: Page 38 (April 1995)

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Abstract: Most patients with allergic asthma experience episodes of bronchoconstriction both early and late after an antigen challenge. The late asthmatic response is a complex inflammatory process mediated in part by specific leukocyte populations recruited to the airways. By study of the late response, many details of the inflammatory cascade have been established, so that histopathologic changes seen in patients with asthma can be explained. These studies also indicate why there is often progression to chronic inflammation in asthma and why therapy for asthma includes anti-inflammatory medication.

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