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Tubulin and microtubes

Berl R. Oakley, C. Elizabeth Oakley
From: Science & Medicine: Volume 2 Number 1: Page 58 (February 1995)

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Abstract: It has long been known that microtubules are composed of tubulin, a stable dimer formed by alpha- and beta-tubulin subunits. The recent discovery of a related molecule, gamma-tubulin, opens the door to deeper understanding of microtubule structure, assembly and disassembly, and organization. Current research indicates that gamma-tubulin is essential for assembly of the mitotic apparatus. As such, it is likely that the new subbunit will provide an additional target for cancer chemotherapy agents.

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