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Strategies for the control of malariaG. Thomas Strickland, Stephen L. Hoffman
Abstract: The most virulent of the four malaria parasite species that infect humans is resistant to drugs in most endemic areas. Eradication of the mosquito vectors with residual insecticides is not a practical possibility. Using insect repellants, screening, and bed nets to prevent transmission is safe and effective but far from universal. Development of new drugs continues, along with attempts to engineer genetically modified mosquitoes. Although development of vaccines against the antigenically complex parasite is a difficult task, recent successful trials give hopethat immunization will provide another weapon in the battle to control malaria. |
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