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Reactive oxygen species: from DNA damage to disease

Marcus S. Cooke, Mark D. Evans
From: Science & Medicine: Volume 10 Number 2: Page 98 (April 2005)

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Abstract: Elevated levels of oxidative DNA damage have been seen in many diseases, but their presence may simply be epiphenomenal rather than pathogenic. Plausible mechanisms have been formulated to describe the role of oxidative DNA damage in the development of these diseases, and the argument for a role of this damage in disease is compelling.

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